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Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria

Low birth weight (LBW) babies account for a large number of neonatal deaths globally, with over 90% of these occurring in developing countries with low resources. Identifying factors that determine survival in these sub-groups of babies in such a low-resource setting will help clinicians prioritize...

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Tác giả chính: Ekwochi U, Ifediora C, Osuorah CDI, Ndu IK, Asinobi IN, Amadi OF, Agwu S, Okeke IB
Định dạng: Other
Năm xuất bản: Enugu State University of Science and Technology, ESUT, Enugu, Nigeria. 2018
Chủ đề:
Technology
Science
Truy cập Trực tuyến:http://lrc.quangbinhuni.edu.vn:8181/dspace/handle/DHQB_123456789/4065
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spelling oai:localhost:DHQB_123456789-40652018-10-22T08:43:08Z Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria Journal of Experimental Research Ekwochi U Ifediora C Osuorah CDI Ndu IK Asinobi IN Amadi OF Agwu S Okeke IB Technology Science Low birth weight (LBW) babies account for a large number of neonatal deaths globally, with over 90% of these occurring in developing countries with low resources. Identifying factors that determine survival in these sub-groups of babies in such a low-resource setting will help clinicians prioritize care and improve outcomes. This study aims to bridge some knowledge gaps in this regard. This was a 45-month prospective study carried out at the Enugu State University Teaching Hospital (ESUTH), Enugu, Nigeria. All eligible newborns weighing between 500g and and lt;2500g that were seen in this period were enrolled and monitored. Data collected were analysed with SPSS Version 24, and significant associations identified using logistic regression models. A total of 166 LBW neonates were enrolled, and 68.2% of them survived. Asphyxia and episodes recurrent apnoea were recorded at least once in 78.8% and 68.4% of the babies respectively, with about two-thirds requiring respiratory support at one time or the other. Survival in these LBW newborns was negatively associated with gestational age at birth of less than 32 weeks (OR 0.17; CI 0.03-0.50; P and lt;0.01) as well as with episodes of recurrent apnoea (OR 0.07; CI 0.02-0.34; P and lt;0.01). However, intra-uterine exposure to malaria was associated with a 15 times higher likelihood of survival (OR 15.41; CI 2.22-106.91; P=0.01). No significant associations was found between survival and attendances to antenatal care, mode of delivery, birth weight and a number of neonatal morbidities like necrotizing enterocolitis, hypothermia, hypoglycaemia, septicaemia, anaemia and neonatal jaundice. Survival rate among low birth weight neonates in a low resource setting is decreased with delivery at less than 32 weeks completed gestation as well as recurrent episodes of apnoea, but is increased with in-utero exposure to malaria. 2018-09-11T02:25:53Z 2018-09-11T02:25:53Z 2017 Other http://lrc.quangbinhuni.edu.vn:8181/dspace/handle/DHQB_123456789/4065 Enugu State University of Science and Technology, ESUT, Enugu, Nigeria.
institution Trung tâm Học liệu Đại học Quảng Bình (Dspace)
collection Trung tâm Học liệu Đại học Quảng Bình (Dspace)
topic Technology
Science
spellingShingle Technology
Science
Ekwochi U
Ifediora C
Osuorah CDI
Ndu IK
Asinobi IN
Amadi OF
Agwu S
Okeke IB
Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria
description Low birth weight (LBW) babies account for a large number of neonatal deaths globally, with over 90% of these occurring in developing countries with low resources. Identifying factors that determine survival in these sub-groups of babies in such a low-resource setting will help clinicians prioritize care and improve outcomes. This study aims to bridge some knowledge gaps in this regard. This was a 45-month prospective study carried out at the Enugu State University Teaching Hospital (ESUTH), Enugu, Nigeria. All eligible newborns weighing between 500g and and lt;2500g that were seen in this period were enrolled and monitored. Data collected were analysed with SPSS Version 24, and significant associations identified using logistic regression models. A total of 166 LBW neonates were enrolled, and 68.2% of them survived. Asphyxia and episodes recurrent apnoea were recorded at least once in 78.8% and 68.4% of the babies respectively, with about two-thirds requiring respiratory support at one time or the other. Survival in these LBW newborns was negatively associated with gestational age at birth of less than 32 weeks (OR 0.17; CI 0.03-0.50; P and lt;0.01) as well as with episodes of recurrent apnoea (OR 0.07; CI 0.02-0.34; P and lt;0.01). However, intra-uterine exposure to malaria was associated with a 15 times higher likelihood of survival (OR 15.41; CI 2.22-106.91; P=0.01). No significant associations was found between survival and attendances to antenatal care, mode of delivery, birth weight and a number of neonatal morbidities like necrotizing enterocolitis, hypothermia, hypoglycaemia, septicaemia, anaemia and neonatal jaundice. Survival rate among low birth weight neonates in a low resource setting is decreased with delivery at less than 32 weeks completed gestation as well as recurrent episodes of apnoea, but is increased with in-utero exposure to malaria.
format Other
author Ekwochi U
Ifediora C
Osuorah CDI
Ndu IK
Asinobi IN
Amadi OF
Agwu S
Okeke IB
author_facet Ekwochi U
Ifediora C
Osuorah CDI
Ndu IK
Asinobi IN
Amadi OF
Agwu S
Okeke IB
author_sort Ekwochi U
title Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria
title_short Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria
title_full Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria
title_fullStr Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria
title_full_unstemmed Determinants of Survival in Low Birth Weight Infants at a Tertiary Healthcare Facility in the South Eastern Nigeria
title_sort determinants of survival in low birth weight infants at a tertiary healthcare facility in the south eastern nigeria
publisher Enugu State University of Science and Technology, ESUT, Enugu, Nigeria.
publishDate 2018
url http://lrc.quangbinhuni.edu.vn:8181/dspace/handle/DHQB_123456789/4065
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score 9,463379

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